Title: Localised Transcriptomes and Proteomes in Neurons
Abstract:
The complex morphology of neurons, with synapses located 100’s of microns from the cell body, necessitates the localization of important cell biological machines and processes within dendrites and axons. I will discuss our studies on the localization of mRNAs and protein synthesis machines — ribosomes — at synapses. In addition, I will describe some of the unique mechanisms neurons use to meet protein demands at synapses.