Probing brains with neuron-inspired electronics

Congratulations to the Lieber lab, which has developed neuron-like electronics that integrate with brain circuitry and record neural spiking activity, as reported in Nature Materials.

Molecular classification of foveal cell types in primate retina

Congratulations to Peng, Shekhar, Yan, Herrmann, Sappington, Bryman, van Zyl, Do, Regev, and Sanes on their paper in Cell! It also is covered in the Gazette.

Linking a mutation to survival in wild mice

Barrett RDH, Laurent S, Mallarino R, Pfeifer SP, Xu CCY, Foll M, Wakamatsu K, Duke-Cohan JS, Jensen JD, Hoekstra HE

Nature Method of the Year 2018: Imaging in freely behaving animals

Congratultations to Aravi Samuel, whose work was cited, and who wrote an accompanying Comment!

Structured Odorant Response Patterns across a Complete Olfactory Receptor Neuron Population

Si G, Kanwal JK, Hu Y, Tabone CJ, Baron J, Berck M1, Vignoud G, Samuel ADT

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, Eggan K

What We Do

Researchers in the Center for Brain Science (CBS) are discovering how brain circuits give rise to computations that underlie thought and behavior. We are determining the structure and function of neural circuits; investigating how these circuits govern behavior and vary between individuals; learning how they change during development and aging; and deepening our understanding of what is amiss in neurological and psychiatric disorders, and how to address these pathologies. To accomplish this mission, CBS brings neuroscientists together with physical scientists and engineers to develop and deploy new tools for neuroscience. Headquartered in the new Northwest Building on Oxford Street in Cambridge, CBS has strong links throughout the neuroscience community at Harvard University. Members are drawn from the Faculty of Arts and Sciences, the Harvard Medical School, the School of Engineering and Applied Sciences, and the Harvard-affiliated hospitals.

Neuroengineering: what tools we need

Neuroimaging: what underlies our thoughts

Light Microscopy: what the brain looks like 

Electron Microscopy: what is the brain's nanostructure

Connectome Project: how the brain is wired

Swartz Program: how do we understand brain function

Education: what training we need