Internal state: dynamic, interconnected communication loops distributed across body, brain, and time

Jessleen K Kanwal, Emma Coddington, Rachel Frazer, Daniela Limbania, Grace Turner, Karla J Davila, Michael A Givens, Valarie Williams, Sandeep Robert Datta, Sara Wasserman

Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validatio

Xuan Huang, Kasper C D Roet, Liying Zhang, Amy Brault, Allison P Berg, Anne B Jefferson, Jackie Klug-McLeod, Karen L Leach, Fabien Vincent, Hongying Yang, Anthony J Coyle, Lyn H Jones, Devlin Frost, Ole Wiskow, Kuchuan Chen, Rie Maeda, Alyssa Grantham, Mary K Dornon, Joseph R Klim, Marco T Siekmann, Dongyi Zhao, Seungkyu Lee, Kevin Eggan, Clifford J Woolf

The pattern of Nodal morphogen signaling is shaped by co-receptor expression

Nathan D Lord, Adam N Carte, Philip B Abitua, Alexander F Schier

An additive algorithm for origami design

Levi H Dudte, Gary P T Choi, L Mahadevan

Beauty is in the eye of the machine.

No abstract available

Mengmi Zhang, Gabriel Kreiman

Accelerating diagnosis of Parkinson's disease through risk prediction

William Yuan, Brett Beaulieu-Jones, Richard Krolewski, Nathan Palmer, Christine Veyrat-Follet, Francesca Frau, Caroline Cohen, Sylvie Bozzi, Meaghan Cogswell, Dinesh Kumar, Catherine Coulouvrat, Bruno Leroy, Tanya Z Fischer, S Pablo Sardi, Karen J Chandross, Lee L Rubin, Anne-Marie Wills, Isaac Kohane, Scott L Lipnick

Algorithms underlying flexible phototaxis in larval zebrafish

Alex B Chen, Diptodip Deb, Armin Bahl, Florian Engert

What We Do

Researchers in the Center for Brain Science (CBS) are discovering how brain circuits give rise to computations that underlie thought and behavior. We are determining the structure and function of neural circuits; investigating how these circuits govern behavior and vary between individuals; learning how they change during development and aging; and deepening our understanding of what is amiss in neurological and psychiatric disorders, and how to address these pathologies. To accomplish this mission, CBS brings neuroscientists together with physical scientists and engineers to develop and deploy new tools for neuroscience. Headquartered in the new Northwest Building on Oxford Street in Cambridge, CBS has strong links throughout the neuroscience community at Harvard University. Members are drawn from the Faculty of Arts and Sciences, the Harvard Medical School, the School of Engineering and Applied Sciences, and the Harvard-affiliated hospitals.

Neuroengineering: what tools we need

Neuroimaging: what underlies our thoughts

Light Microscopy: what the brain looks like 

Electron Microscopy: what is the brain's nanostructure

Connectome Project: how the brain is wired

Swartz Program: how do we understand brain function

Education: what training we need