NeuroPAL: A Multicolor Atlas for Whole-Brain Neuronal Identification in C. elegans

Eviatar Yemini , Albert Lin , Amin Nejatbakhsh , Erdem Varol , Ruoxi Sun , Gonzalo E Mena , Aravinthan D T Samuel , Liam Paninski , Vivek Venkatachalam , Oliver Hobert

Distinct temporal difference error signals in dopamine axons in three regions of the striatum in a decision-making task

Iku Tsutsui-Kimura , Hideyuki Matsumoto , Korleki Akiti , Melissa M Yamada , Naoshige Uchida , Mitsuko Watabe-Uchida

Neuron class-specific responses govern adaptive myelin remodeling in the neocortex

Sung Min Yang, Katrin Michel , Vahbiz Jokhi , Elly Nedivi , Paola Arlotta

Continuous Whole-Body 3D Kinematic Recordings across the Rodent Behavioral Repertoire

Jesse D Marshall , Diego E Aldarondo , Timothy W Dunn , William L Wang , Gordon J Berman , Bence P Ölveczky

Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior

Yvonne Kölsch , Joshua Hahn , Anna Sappington , Manuel Stemmer , António M Fernandes , Thomas O Helmbrecht , Shriya Lele , Salwan Butrus , Eva Laurell , Irene Arnold-Ammer , Karthik Shekhar , Joshua R Sanes , Herwig Baier

History of conditioned reward association disrupts inhibitory control: an examination of neural correlates

Kristin N Meyer , Juliet Y Davidow , Koene R A Van Dijk,  Rosario M Santillana , Jenna Snyder , Constanza M Vidal Bustamante , Marissa Hollinshead , Bruce R Rosen , Leah H Somerville , Margaret A Sheridan

What We Do

Researchers in the Center for Brain Science (CBS) are discovering how brain circuits give rise to computations that underlie thought and behavior. We are determining the structure and function of neural circuits; investigating how these circuits govern behavior and vary between individuals; learning how they change during development and aging; and deepening our understanding of what is amiss in neurological and psychiatric disorders, and how to address these pathologies. To accomplish this mission, CBS brings neuroscientists together with physical scientists and engineers to develop and deploy new tools for neuroscience. Headquartered in the new Northwest Building on Oxford Street in Cambridge, CBS has strong links throughout the neuroscience community at Harvard University. Members are drawn from the Faculty of Arts and Sciences, the Harvard Medical School, the School of Engineering and Applied Sciences, and the Harvard-affiliated hospitals.

Neuroengineering: what tools we need

Neuroimaging: what underlies our thoughts

Light Microscopy: what the brain looks like 

Electron Microscopy: what is the brain's nanostructure

Connectome Project: how the brain is wired

Swartz Program: how do we understand brain function

Education: what training we need