Zebrafish – An Animal That “Sees”


February 25, 2015 - 1:00pm
NW 243
About the Speaker
John Dowling

Zebrafish respond robustly to a wide variety of visual stimuli. Their retinas contain rods and four classes of cones that are arranged in a precise mosaic. They can be manipulated genetically, and are a marvelous model system for the study of retinal mechanisms. In this talk, I shall describe various behavioral tests we have developed to evaluate their vision and illustrate this with a brief discussion of one mutant whose photoreceptor synaptic terminals have an interesting and specific defect. I will close with a brief discussion of zebrafish cones, their connectivity with second-order cells and one role for the UV-sensitive cones.