Hippocampal memory reactivation and reward

Summary

Date: 
November 25, 2014 - 1:00pm
Location: 
NW 243
About the Speaker
Name: 
Matt Wilson (MIT)

By introducing arrays of microelectrodes into hippocampal, subcortical, and neocortical areas of freely behaving rodents, we have characterized the detailed structure and content of memory patterns across ensembles of individual neurons as they are formed during spatial behavior, and reactivated during quiet wakefulness, and sleep. I will discuss the relationship between the memory reactivation in hippocampus and reward signaling in the VTA, and the impact of hippocampal manipulation during goal directed behavior.