A Grid in the Brain

Summary

Date: 
November 17, 2016 - 2:00pm - 3:00pm
Location: 
Northwest 425
About the Speaker
Name: 
Saikat Ray
Speaker Affiliation: 
Bernstein Center for Computational Neuroscience, Berlin; Humboldt University, Berlin

Abstract:

The analysis of spatial cells in the hippocampus and the medial entorhinal cortex has been a remarkable success story. Extracellular recordings have revealed astonishing functional abstractness in how single neurons encode concepts such as a place, direction, borders and grids. Though we know a great deal about these functional phenotypes of neuronal activation, information about their underlying microcircuits is sorely lacking. In this talk I will explore the structural underpinnings of this functional specificity in the superficial layers of the medial entorhinal cortex and what the components and architecture of the microcircuits involved in this reveal across evolution and development.